KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTRA2
All Species:
20
Human Site:
T231
Identified Species:
44
UniProt:
O43464
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43464
NP_037379.1
458
48841
T231
D
P
V
A
D
I
A
T
L
R
I
Q
T
K
E
Chimpanzee
Pan troglodytes
XP_508084
598
64926
L371
D
E
K
A
D
I
A
L
I
K
I
D
H
Q
G
Rhesus Macaque
Macaca mulatta
XP_001110803
458
48732
T231
D
P
V
A
D
I
A
T
L
R
I
Q
T
K
E
Dog
Lupus familis
XP_532992
199
21668
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIY5
458
49330
T231
D
P
V
A
D
I
A
T
L
R
I
Q
T
K
E
Rat
Rattus norvegicus
NP_001100069
458
49076
T231
D
P
V
A
D
I
A
T
L
R
I
Q
T
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420813
466
50374
T243
D
K
K
S
D
I
A
T
I
K
I
H
P
K
K
Frog
Xenopus laevis
NP_001088796
457
48812
L230
D
E
K
A
D
I
A
L
I
K
I
K
A
K
G
Zebra Danio
Brachydanio rerio
XP_001339411
294
31781
S84
T
L
R
L
G
K
S
S
D
V
R
Q
G
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFJ3
422
45981
S208
S
V
M
R
L
G
K
S
S
T
L
R
S
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3E6S8
459
49256
L236
D
L
Q
S
D
I
A
L
V
K
I
K
S
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.9
99.1
41.7
N.A.
84.9
87.3
N.A.
N.A.
40.9
41
43.6
N.A.
42.3
N.A.
N.A.
N.A.
Protein Similarity:
100
52.5
99.1
42.5
N.A.
89.3
91.4
N.A.
N.A.
59.4
59.1
54.3
N.A.
59.3
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
0
N.A.
100
100
N.A.
N.A.
46.6
46.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
0
N.A.
100
100
N.A.
N.A.
73.3
66.6
26.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
55
0
0
73
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
73
0
0
0
73
0
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
19
0
0
0
0
0
0
0
0
0
0
0
10
46
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
0
0
10
10
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
0
0
0
73
0
0
28
0
73
0
0
0
0
% I
% Lys:
0
10
28
0
0
10
10
0
0
37
0
19
0
64
10
% K
% Leu:
0
19
0
10
10
0
0
28
37
0
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
37
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
46
0
10
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
37
10
10
0
0
0
% R
% Ser:
10
0
0
19
0
0
10
19
10
0
0
0
19
0
0
% S
% Thr:
10
0
0
0
0
0
0
46
0
10
0
0
37
0
10
% T
% Val:
0
10
37
0
0
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _